Live human neuronal circuits in a petri dish

Our lab has established a platform in vitro to facilitate the discovery and validation of treatments for brain disorders.  Our research is at the frontier of human cellular neuroscience research and translational applications that benefit global public health. 

Human iPSC-derived neuronal models

The large majority of the work in our lab is based on human neuronal cultures derived from induced pluripotent stem cells (iPSC). New cell-reprogramming technologies provide us with an unique advantage to study human neuronal physiology in health and disease. 

Parkinson's disease

We investigate the neurobiological and genetic predispositions of Parkinson's with iPSC-derived neuronal models. 

Cell biology, electrophysiology, single-cell transcriptomics and bioinformatics

Our multidisciplinary analytical approach combines many technical expertise, including: tissue culture​, patch-clamping, live imaging, genomics, , flow cytometry,  molecular biology, machine learning analysis and bioinformatics.

Brain Cancer

We investigate the biological properties of patient-derived glioblastoma cells and their interaction with neuronal microenvironment. ​

SAHMRI Mind & Brain


Our lab is  located in the iconic South Australian Health and Medical Research Institute (SAHMRI Mind & Brain theme) in Adelaide and affiliated with the College of Medicine and Public Health (Flinders University). 

SAHMRI is a new, vibrant medical research institute, which houses 600 international scientists. The state-of-the-art research facility and cores provide an outstanding environment for scientific discoveries.

The strong collaborative research community within SAHMRI, local universities and international partners fosters an exceptional environment where scientists can thrive to the best of their creativity and productivity.

SAHMRI highly benefits from the close partnership with 3 major local universities and a total of 90,000 students: Flinders University, The University of Adelaide, The University of South Australia.

Finally, SAHMRI and our lab are essentially oriented towards translational applications. SAHMRI's central location in the Biomed city, beside the ultramodern Royal Adelaide Hospital, stimulates fruitful collaborations with clinicians and patients.
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